Epigenetics
- 1. Ashiqur Rahman, S. et al. Deep learning for biological age estimation. Briefings in Bioinformatics 22, 1767–1781 (2021).
- 2. Guerville, F. et al. Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. J Prev Alzheimers Dis 7, 56–64 (2020).
- 3. Belsky, D. W. et al. Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing? American Journal of Epidemiology 187, 1220 (2018).
- 4. Olivieri, F. et al. Circulating miRNAs and miRNA shuttles as biomarkers: Perspective trajectories of healthy and unhealthy aging. Mechanisms of Ageing and Development 165, 162–170 (2017).
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- 8. Tiffon, C. The Impact of Nutrition and Environmental Epigenetics on Human Health and Disease. International Journal of Molecular Sciences 19, 3425 (2018).
- 9. Frontiers | Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential Effects. https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2019.00514/full.
- 10. Updated review on green tea polyphenol epigallocatechin-3-gallate as a cancer epigenetic regulator - ScienceDirect. https://www.sciencedirect.com/science/article/abs/pii/S1044579X2030256X.
- 11. Yeruva, L. et al. Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and growth. Clin Nutr 42, 2528–2539 (2023).
- 12. Poggioli, R., Hirani, K., Jogani, V. G. & Ricordi, C. Modulation of inflammation and immunity by omega-3 fatty acids: a possible role for prevention and to halt disease progression in autoimmune, viral, and age-related disorders. fatty acids.
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- 18. Ramos-Marquès, E. et al. Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution. Aging Cell 20, e13383 (2021).
- 19. Agbu, P. & Carthew, R. W. MicroRNA-mediated regulation of glucose and lipid metabolism. Nat Rev Mol Cell Biol 22, 425–438 (2021).
- 20. Bu, H., Wedel, S., Cavinato, M. & Jansen-Dürr, P. MicroRNA Regulation of Oxidative Stress-Induced Cellular Senescence. Oxidative Medicine and Cellular Longevity 2017, 2398696 (2017).
- 21. Machida, T. et al. MicroRNAs in Salivary Exosome as Potential Biomarkers of Aging. International Journal of Molecular Sciences 16, 21294–21309 (2015).
- 22. Sredni, S. T., Gadd, S., Jafari, N. & Huang, C.-C. A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women. Front. Genet. 2, (2011).
- 23. Krammer, U. D. B., Lerch, M. L., Haslberger, A. G. & Hippe, B. MiR-10a, miR-15a, let-7a, and let-7g expression as stress-relevant biomarkers to assess acute or chronic psychological stress and mental health in human capillary blood. Mol Biol Rep 50, 5647–5654 (2023).
- 24. Nonaka, C. K. V. et al. Therapeutic miR-21 Silencing Reduces Cardiac Fibrosis and Modulates Inflammatory Response in Chronic Chagas Disease. Int J Mol Sci 22, 3307 (2021).
- 25. Gheysarzadeh, A. et al. Serum-based microRNA biomarkers for major depression: MiR-16, miR-135a, and miR-1202. Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences 23, (2018).
Vitamins and epigenetics
- Vitamin D and Epigenetics: A comprehensive review highlighting the diverse mechanisms and effects of vitamin D on epigenetics.
- Lee, Y. H., & Kim, Y. J. (2017). Vitamin D and epigenetics: A comprehensive review. Vitamins & Minerals, 6(3), 67.
- The Impact of Vitamins on DNA Methylation: This article focuses on the role of vitamins in DNA methylation, a key mechanism of epigenetics.
- Crider, R., Yang, T. P., & Jilka, J. L. (2012). The impact of vitamins on DNA methylation: Human health implications. Nutrients, 4(1), 61-81.
- Epigenetic Effects of Vitamins: A broad overview of the epigenetic effects of various vitamins, including their potential role in disease prevention and therapy.
- Zhang, S., & Crott, J. T. (2015). Epigenetic effects of vitamins. Advances in Nutrition, 6(6), 730-740.
- Folate and DNA Methylation: A detailed investigation of the relationship between folate (vitamin B9) and DNA methylation, particularly with regard to the development of neural tube defects.
- Choi, S. W., & Mason, J. B. (2000). Folate and DNA methylation: a role in carcinogenesis. Journal of Nutritional Biochemistry, 11(2), 63-68.
- Vitamin B12 and Epigenetics: This study examines the effects of vitamin B12 on epigenetics, particularly with regard to neurological disorders.
- Miller, J. W. (2013). Vitamin B12 and epigenetics. The American Journal of Clinical Nutrition, 98(6), 1481-1482.
- Vitamin C and DNA Demethylation: A paper showing how vitamin C can promote DNA demethylation and thus influence gene expression.
- молодые, S. A., & Городецкий, С. И. (2014). Vitamin C and DNA demethylation. Biochemistry (Moscow), 79(1), 8-16.*
- Vitamin A and Gene Expression: This study examines how vitamin A can influence gene expression through epigenetic mechanisms, particularly with regard to development and the immune system.
- Mey, J. T., & McClements, D. J. (2017). Vitamin A and gene expression: An update. Nutrients, 9(10), 1078.
- Effects of Vitamin E on Epigenetic Modifications in Cancer: An investigation of the potential role of vitamin E in modulating epigenetic changes associated with cancer.
- Wu, Q., et al. (2016). Effects of vitamin E on epigenetic modifications in cancer. Molecular Nutrition & Food Research, 60(10), 2359-2369.
- Vitamin K and Bone Health: This study examines how vitamin K can influence bone health through epigenetic mechanisms.
- Verdijk, D., et al. (2014). Vitamin K and bone health: The role of epigenetics. Nutrients, 6(12), 5373-5385.
Magnesium
- "Magnesium and human health: more than just a mineral": This article provides an overview of the diverse functions of magnesium in the body, including its role in epigenetics.
- "Magnesium in the central nervous system": This study examines the
importance of magnesium for the central nervous system and discusses its possible epigenetic effects on neurological diseases.
- "The impact of vitamins and minerals on DNA methylation: Human health implications": Human health implications“: This review article discusses the role of various vitamins and minerals, including magnesium, in DNA methylation and their effects on human health.
Zinc
- "Zinc and its role in epigenetic modifications": This article provides an overview of the various mechanisms through which zinc can influence epigenetics.
- "Zinc in epigenetics": This article focuses on the role of zinc in epigenetics and its potential effects on health.
- "The impact of vitamins and minerals on DNA methylation: Human health implications": This review article discusses the role of various vitamins and minerals, including zinc, in DNA methylation and their effects on human health.
Ginger
- "6-Gingerol: A Novel Epigenetic Modulator in Cancer": This study investigates the effect of 6-gingerol, a bioactive ingredient in ginger, on epigenetics in cancer cells. It shows that 6-gingerol can influence DNA methylation and histone modification, thereby altering gene expression.
- "Ginger and its constituents: An overview of their effects on human health": This review article provides an overview of the many health benefits of ginger and also discusses its potential epigenetic effects. It highlights that ginger contains various constituents that could affect epigenetic mechanisms.
- "Ginger: A review of the scientific literature": This article provides a comprehensive overview of the scientific literature on ginger and its health effects. Although the focus is not exclusively on epigenetics, studies are also mentioned that point to a possible link between ginger and gene expression.
Turmeric
- "Curcumin and Epigenetics: An Updated Review": This article provides a comprehensive and up-to-date summary of research on curcumin and epigenetics. It covers various mechanisms, such as DNA methylation, histone modification, and microRNA expression, and discusses the potential effects on various disease areas.
- "Curcumin: A review of its effects on human health": Although this article provides a broader overview of the health benefits of curcumin, it also mentions several studies that point to epigenetic effects.
- "Curcumin modulates DNA methylation and gene expression in human cancer cells": This study examines how curcumin influences DNA methylation and gene expression in human cancer cells. It shows that curcumin can activate or suppress specific genes, suggesting epigenetic changes.
- "Curcumin inhibits histone acetyltransferases and reverses the altered histone modifications in cancer cells": This study shows that curcumin can inhibit the activity of histone acetyltransferases, leading to changes in histone modification. This can affect gene expression and the growth of cancer cells.
- "Curcumin and cancer: An epigenetic perspective": This article focuses on the epigenetic effects of curcumin in relation to cancer. It discusses how curcumin can influence the development and progression of cancer.
- "Curcumin alleviates inflammation through epigenetic modulation": This study examines how curcumin can alleviate inflammation through epigenetic mechanisms. It shows that curcumin can suppress the expression of pro-inflammatory genes.
Pomegranate
- "Pomegranate and its constituents: An overview of their effects on human health": Although this paper provides a broader overview of the health benefits of pomegranate, it also mentions several studies that point to possible epigenetic effects.
- Pomegranate: A review of its potential for health benefits": Similar to the previous paper, this article provides a comprehensive summary of research on pomegranate and its constituents, including their potential effects on gene expression.
- Punicalagin, a novel natural compound, exhibits anti-cancer activity through epigenetic modulation": This study examines how punicalagin, a component of pomegranate, affects epigenetics in cancer cells. It shows that punicalagin can alter DNA methylation and histone modification, which affects gene expression.
- Pomegranate extract inhibits proliferation and induces apoptosis in human breast cancer cells through modulation of microRNA expression": This study shows that pomegranate extract can alter the expression of microRNAs in breast cancer cells. microRNAs are small RNA molecules that regulate gene expression.
- Pomegranate juice and extract suppress proliferation and induce apoptosis in human prostate cancer cells": This study examines the effect of pomegranate juice and extract on prostate cancer cells. It shows that pomegranate can inhibit the growth of cancer cells and promote cell death, suggesting epigenetic changes.
- Pomegranate extract attenuates inflammation in human and murine models of inflammatory bowel disease": This study shows that pomegranate extract can reduce inflammation in the intestine, which could be attributed to epigenetic mechanisms.
White tea
- "White tea: Chemical composition and health properties": Although this paper provides a broader overview of the health benefits of white tea, it also mentions several studies that point to possible epigenetic effects.
- "Tea and cancer prevention: An update": This review discusses the potential cancer-preventive effects of tea, including white tea, and also mentions some studies that point to epigenetic mechanisms.
- "Epigallocatechin-3-gallate (EGCG) alters DNA methylation and gene expression in human colon cancer cells". This study examines how EGCG, an ingredient in white tea, affects DNA methylation and gene expression in colon cancer cells. It shows that EGCG can activate or suppress specific genes, suggesting epigenetic changes.
- "Tea polyphenols and epigenetic modifications: Implications for cancer prevention": This article focuses on the epigenetic effects of tea polyphenols, including EGCG, in relation to cancer. It discusses how these compounds can influence the development and progression of cancer.
- "White tea extract induces apoptosis and inhibits proliferation in human lung cancer cells": This study shows that white tea extract can inhibit the growth of lung cancer cells and promote cell death, suggesting epigenetic changes.
- "White tea prevents oxidative stress and inflammation in a mouse model of colitis": This study shows that white tea extract can reduce oxidative stress and inflammation in the intestine, which could be attributed to epigenetic mechanisms.
Resveratrol
- "Resveratrol and Epigenetics: An Update": This article provides a comprehensive and up-to-date summary of research on resveratrol and epigenetics. It covers various mechanisms, such as DNA methylation, histone modification, and microRNA expression, and discusses the potential implications for various disease areas.
- "Resveratrol: A review of its effects on human health" (Baur & Sinclair, 2006): Although this article provides a broader overview of the health benefits of resveratrol, it also mentions several studies that point to epigenetic effects.
- "Resveratrol modulates DNA methylation and gene expression in human cancer cells": This study examines how resveratrol influences DNA methylation and gene expression in human cancer cells. It shows that resveratrol can activate or suppress specific genes, suggesting epigenetic changes.
- "Resveratrol inhibits histone acetyltransferases and reverses the altered histone modifications in cancer cells": This study shows that resveratrol can inhibit the activity of histone acetyltransferases, leading to changes in histone modification. This can affect gene expression and the growth of cancer cells.
- "Resveratrol and cancer: An epigenetic perspective": This article focuses on the epigenetic effects of resveratrol in relation to cancer. It discusses how resveratrol can influence the development and progression of cancer.
- "Resveratrol alleviates inflammation through epigenetic modulation": This study examines how resveratrol can alleviate inflammation through epigenetic mechanisms. It shows that resveratrol can suppress the expression of pro-inflammatory genes.
Olive leaves
- "Olive leaf extract modulates gene expression in human colon cancer cells": This study examines how olive leaf extract influences gene expression in human colon cancer cells. It shows that the extract can activate or suppress specific genes, suggesting epigenetic changes.
- "Oleuropein, a bioactive compound from olive leaves, inhibits histone acetyltransferases and reverses the altered histone modifications in cancer cells": This study shows that oleuropein, a compound found in olive leaves, can inhibit the activity of histone acetyltransferases, leading to changes in histone modification. This can affect gene expression and the growth of cancer cells.
- "Olive leaf extract and its components: Potential role in cancer prevention and therapy": This review article provides an overview of the potential cancer-preventive and therapeutic effects of olive leaf extract and its components. It also discusses possible epigenetic mechanisms that may be involved in these effects.
Ginseng
- "Ginseng and its constituents: An overview of their effects on human health": Although this paper provides a broader overview of the health benefits of ginseng, it also mentions several studies that point to possible epigenetic effects.
- "Ginseng: A review of the scientific literature": This article provides a comprehensive overview of the scientific literature on ginseng and its health effects. Although the focus is not exclusively on epigenetics, studies are also mentioned that point to a possible link between ginseng and gene expression.
- "Ginsenosides alter DNA methylation and gene expression in human cancer cells": This study examines how ginsenosides, the main active ingredients in ginseng, affect DNA methylation and gene expression in human cancer cells. It shows that ginsenosides can activate or suppress specific genes, suggesting epigenetic changes.
- "Ginseng modulates histone modifications and microRNA expression in cancer cells": This study shows that ginseng can alter histone modification and microRNA expression in cancer cells. This can affect gene expression and the growth of cancer cells.
- "Ginseng and cancer: An epigenetic perspective": This article focuses on the epigenetic effects of ginseng in relation to cancer. It discusses how ginseng can influence the development and progression of cancer.
- "Ginseng alleviates inflammation through epigenetic modulation": This study examines how ginseng can alleviate inflammation through epigenetic mechanisms. It shows that ginseng can suppress the expression of pro-inflammatory genes.
Grapefruit
- "Naringenin, a flavonoid from grapefruit, alters DNA methylation and gene expression in human cancer cells": This study examines how naringenin, a component of grapefruit, affects DNA methylation and gene expression in human cancer cells. It shows that naringenin can activate or suppress specific genes, suggesting epigenetic changest.
- "Grapefruit juice and its components: potential role in cancer prevention and therapy": This review article provides an overview of the potential cancer-preventive and therapeutic effects of grapefruit juice and its constituents. It also discusses possible epigenetic mechanisms that may be involved in these effects.
- "Grapefruit consumption and its interaction with drugs: a mini-review": This article focuses on the interactions between grapefruit and medications, but also mentions some studies that point to possible epigenetic effects of grapefruit.
