{"id":25981217,"date":"2025-11-27T13:20:57","date_gmt":"2025-11-27T13:20:57","guid":{"rendered":"https:\/\/www.nutagen.com\/detailed-evaluation\/"},"modified":"2026-03-06T07:43:31","modified_gmt":"2026-03-06T07:43:31","slug":"podrobne-hodnoceni","status":"publish","type":"page","link":"https:\/\/nutagen.com\/cs\/podrobne-hodnoceni\/","title":{"rendered":"Podrobn\u00e9 hodnocen\u00ed"},"content":{"rendered":"
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Podrobn\u00e9 hodnocen\u00ed<\/h1><\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n
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Nutagen Nutrigenetics pou\u017e\u00edv\u00e1 k ur\u010den\u00ed intervence mnohem komplexn\u011bj\u0161\u00ed a p\u0159esn\u011bj\u0161\u00ed z\u00e1kladn\u00ed data ne\u017e personalizovan\u00e9 produkty konkurence. Sou\u010dasn\u00ed poskytovatel\u00e9 analyzuj\u00ed pouze statick\u00e9 a levn\u00e9 GEN SNP (jednonukleotidov\u00e9 polymorfismy) ve spojen\u00ed s vyhodnocen\u00edm dotazn\u00edku z\u00e1kazn\u00edka, aby mohli vyvinout sv\u00e9 produkty. Takov\u00e9 genetick\u00e9 testy neumo\u017e\u0148uj\u00ed jednozna\u010dn\u00e9 posouzen\u00ed epigenetick\u00e9 reakce jednotlivce.<\/p>\n

Nutagen jde rozhoduj\u00edc\u00edm krokem d\u00e1le a analyzuje p\u0159edev\u0161\u00edm v\u00fdznamn\u00fd v\u00fdb\u011br epigenetick\u00fdch faktor\u016f. Pouze kombinace vybran\u00fdch z\u00e1kladn\u00edch \u00fadaj\u016f s p\u0159esnou anal\u00fdzou \u201eepigenetick\u00e9 = dynamick\u00e9 odchylky\u201c individu\u00e1ln\u00edho pl\u00e1nu odhal\u00ed, kter\u00e9 geny lze reaktivovat\/deaktivovat a\/nebo opravit pomoc\u00ed kter\u00fdch fytonutrient\u016f. Tento holistick\u00fd panel je zalo\u017een na nejnov\u011bj\u0161\u00edm v\u011bdeck\u00e9m v\u00fdzkumu a byl d\u016fkladn\u011b ov\u011b\u0159en (*ov\u011b\u0159ovac\u00ed studie HealthBioCare NUTAGEN z \u0159\u00edjna 2024).<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n

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1. Anal\u00fdza vybran\u00fdch genov\u00fdch SNP<\/h2><\/div><\/div>\n<\/div>\n<\/div>\n\n
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Bylo zji\u0161t\u011bno, \u017ee SNP hraj\u00ed v\u00fdznamnou roli ve v\u00fdvoji a progresi r\u016fzn\u00fdch onemocn\u011bn\u00ed. V\u011bdci vyu\u017e\u00edvaj\u00ed SNP k identifikaci genetick\u00fdch variant spojen\u00fdch s konkr\u00e9tn\u00edmi onemocn\u011bn\u00edmi. To vedlo k objevu gen\u016f spojen\u00fdch s r\u016fzn\u00fdmi onemocn\u011bn\u00edmi, v\u010detn\u011b srde\u010dn\u00edch onemocn\u011bn\u00ed, rakoviny, du\u0161evn\u00edch poruch (nap\u0159. schizofrenie, deprese) a autoimunitn\u00edch onemocn\u011bn\u00ed (nap\u0159. lupus) v l\u00e9ka\u0159sk\u00e9m v\u00fdzkumu.<\/p>\n

Identifikace SNP tak\u00e9 umo\u017e\u0148uje p\u0159izp\u016fsobit l\u00e9\u010dbu individu\u00e1ln\u00edm genetick\u00fdm charakteristik\u00e1m dan\u00e9 osoby..<\/p>\n

1. FTO (gen spojen\u00fd s tukovou hmotou a obezitou)<\/strong>
Gen FTO ovliv\u0148uje regulaci t\u011blesn\u00e9 hmotnosti a hromad\u011bn\u00ed tuku. Hraje roli v kontrole chuti k j\u00eddlu a energetick\u00e9 rovnov\u00e1hy t\u00edm, \u017ee reguluje v\u00fddej energie a pocit hladu.<\/p>\n

2.MTHFR (methylentetrahydrofol\u00e1t redukt\u00e1za)<\/strong>
SNP MTHFR (methylentetrahydrofol\u00e1t redukt\u00e1za) odkazuje na genetick\u00e9 varianty v genu MTHFR, kter\u00fd je zodpov\u011bdn\u00fd za produkci enzymu zvan\u00e9ho methylentetrahydrofol\u00e1t redukt\u00e1za. Tento enzym hraje \u00fast\u0159edn\u00ed roli v metabolismu fol\u00e1tu (vitam\u00ednu B9), kter\u00fd je nezbytn\u00fd pro procesy, jako je d\u011blen\u00ed bun\u011bk, oprava DNA a produkce d\u016fle\u017eit\u00fdch molekul v t\u011ble. Je tak\u00e9 z\u00e1sadn\u00ed pro p\u0159em\u011bnu homocysteinu na methionin, aminokyselinu, kter\u00e1 je d\u016fle\u017eit\u00e1 pro synt\u00e9zu b\u00edlkovin a ochranu bun\u011bk.<\/p>\n

3. FADS1 (desatur\u00e1za mastn\u00fdch kyselin 1)<\/strong>
TGen FADS1 k\u00f3duje enzym, kter\u00fd umo\u017e\u0148uje p\u0159em\u011bnu omega-3 a omega-6 mastn\u00fdch kyselin na jejich aktivn\u00ed formy (EPA a DHA). Tyto mastn\u00e9 kyseliny jsou z\u00e1sadn\u00ed pro bun\u011b\u010dn\u00e9 membr\u00e1ny, mozek a protiz\u00e1n\u011btliv\u00e9 procesy.<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n

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2. P\u0159esn\u00e1 anal\u00fdza specifick\u00fdch epigenetick\u00fdch biomarker\u016f (mikroRNA)<\/h2><\/div><\/div>\n<\/div>\n<\/div>\n\n
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Anal\u00fdza Nutagen se zam\u011b\u0159uje zejm\u00e9na na relativn\u011b nezn\u00e1m\u00e9, ale velmi zaj\u00edmav\u00e9 molekuly zn\u00e1m\u00e9 jako mikroRNA nebo miRNA (mikro ribonukleov\u00e9 kyseliny). Jedn\u00e1 se o nov\u011b objeven\u00e9 biomarkery, kter\u00e9 pln\u00ed velmi d\u016fle\u017eit\u00e9 kl\u00ed\u010dov\u00e9 funkce v regulaci biologick\u00fdch proces\u016f, jako je proliferace, diferenciace, bun\u011b\u010dn\u00fd cyklus a apopt\u00f3za. Objev a funk\u010dnost t\u011bchto molekul byly v roce 2024 ocen\u011bny Nobelovou cenou za medic\u00ednu<\/a>.<\/p>\n<\/div><\/div>\n\n

miRNA se v\u00e1\u017eou na messengerRNA (mRNA) a t\u00edm inhibuj\u00ed biosynt\u00e9zu protein\u016f, \u010d\u00edm\u017e sni\u017euj\u00ed mno\u017estv\u00ed protein\u016f v bu\u0148ce. Dosud bylo identifikov\u00e1no v\u00edce ne\u017e 2000 miRNA, kter\u00e9 reguluj\u00ed asi jednu t\u0159etinu v\u0161ech gen\u016f k\u00f3duj\u00edc\u00edch proteiny. N\u00e1sleduj\u00edc\u00ed miRNA jsou individu\u00e1ln\u011b vyhodnocov\u00e1ny pomoc\u00ed laboratorn\u00edho testu:<\/p>\n